搜狗做题网英语翻译Before Gleevec came along,the average survival for a pat
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英语翻译
Before Gleevec came along,the average survival for a patient diagnosed with CML was about four to six years.Interferon,the standard therapy for CML,could prolong survival for another one or two years,if a patient could tolerate it or was among the few who responded well.In the four years since Gleevec has been on the market,only 16 percent of newly diagnosed patients on Gleevec have relapsed."If those numbers stay on track,the average survival could be in the 15- to 20-year range," notes Dr.Druker,director of Oregon Health & Science University's Center for Hematologic Malignancies."That's a huge difference." It turns out that because the enzyme that drives the growth of a kind of stomach cancer called gastrointestinal stromal cancer (GIST) is similar to the enzyme at work in CML,Gleevec has also turned the prognosis of that disease around."Before Gleevec,there was no effective treatment for GIST," says Dr.Druker.If the tumor wasn't operable,or the surgeon couldn't remove the entire tumor,patients lived an average of one to two years after diagnosis.More than half of the GIST patients taking Gleevec show little sign of active disease.
Before Gleevec came along,the average survival for a patient diagnosed with CML was about four to six years.Interferon,the standard therapy for CML,could prolong survival for another one or two years,if a patient could tolerate it or was among the few who responded well.In the four years since Gleevec has been on the market,only 16 percent of newly diagnosed patients on Gleevec have relapsed."If those numbers stay on track,the average survival could be in the 15- to 20-year range," notes Dr.Druker,director of Oregon Health & Science University's Center for Hematologic Malignancies."That's a huge difference." It turns out that because the enzyme that drives the growth of a kind of stomach cancer called gastrointestinal stromal cancer (GIST) is similar to the enzyme at work in CML,Gleevec has also turned the prognosis of that disease around."Before Gleevec,there was no effective treatment for GIST," says Dr.Druker.If the tumor wasn't operable,or the surgeon couldn't remove the entire tumor,patients lived an average of one to two years after diagnosis.More than half of the GIST patients taking Gleevec show little sign of active disease.
在Gleevec出现之前,被诊断为CML的病人平均存活时间为4到6年.治疗CML的标准疗法--干扰素,对于可以忍受或少数反应良好的病人,它可以使生命延长1到2年.Gleevec投放市场4 年来,服用它的病人只有16%复发.俄勒冈州健康与科学大学恶性血液病中心主任Druker博士说：“如果这个数字能够保持,那么（病人）平均存活时间可以在15--20年这个范围,这是一个巨大的差异.”由于CML中起作用的酶与促进胃肠道基质癌（GIST）生长的酶类似,Gleevec也使这种病的预后（即对病情发展的预测）扭转.他说“Gleevec之前,对GIST没有有效的治疗方法”如果肿瘤不能做手术,或者外科医生不能将肿瘤完全切除,病人在确诊后平均存活1到2年.服用Gleevec的GIST病人有轻微活动性疾病的症状.
CML：慢性粒细胞白血病
CML：慢性粒细胞白血病
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