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请大家帮忙翻译一段话(和核磁共振有关),万分感谢呀
Compound 7 was assigned the molecular formula C30H48O3 by HRESIMS. Analysis of the 1H and 13C NMR spectra (Table 2) indicated 7 and 6 had the same lanostane skeleton, but a different side chain. The NMR data for the side chain part,resonances for two methyls [δH 1.89 (3H, s), δC 17.4; δH 0.96
(3H, d, J = 6.8 Hz), δC 12.9], two methylenes including one olefinic methylene [δH 6.02 (1H, s), 5.85 (1H, s); δC 125.8],two methines including one oxymethine [δH 4.17 (1H, m); δC 69.3], two quaternary carbons including one olefinic carbon (δC144.7), and one carbonyl carbon (δC 203.4), which were similar to those of inonotsutriols D and E,10 indicated 7 was the 24-oxo derivative of inonotsutriol D or E. This was proven by 2D NMR data analysis, particularly by the correlations by HMBC from H-22 to C-24; from H2-23 to C-24; from H-26b (δH 5.85) to C-24, C-25, and Me-27; and from H3-27 to C-24, C-25, and C-26. The relative configuration of 7 was proven by ROESY.The correlations between H-3/H3-28 indicated H-3 was α-oriented.10 Therefore, inonotusol G was designated as 3β,22-dihydroxy-5α-lanosta-8,25-dien-24-one. We have tried to determine the absolute configuration of C-22 by application
of the modified Mosher’s method,3 but failed. The derivative of (S)- or (R)-MTPA esters for the hydroxy group at C-22 could not be obtained from 7 using (−)- or (+)-MTPACl (α-methoxy-α trifluoromethylphenylacetyl chloride) by stirring atroom temperature for 24 h or heating at 60 °C for 30 min. The hydrogen bond effect between the carbonyl group at C-24 and the hydroxy group at C-22 may have hindered the reactions.
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7 种化合物被指派分子式 C30H48O3,HRESIMS。1h 和 13c 核磁共振谱 (表 2) 分析表明,7 和 6 有相同的甾具骷髅,但是不同的侧链。侧链的核磁共振数据部分,两个甲基的共振 [δH 1.89 3 H s),δC 17.4; δH 0.96
(3 H、 d、 J = 6.8 Hz),δC 12.9],包括一个烯亚甲基的两个链 [δH 6.02 (1 H、 s) 5.85 1 H s) ;δC 1258],包括一个 oxymethine [δH 4.17 (1 H、 m) ; δC 69.3],包括一个烯碳 (δC144.7) 和一个羰基碳 (δC 203.4),类似于 inonotsutriols D 和 E 的两个第四纪碳原子的两个甲烯,10 表示 7inonotsutriol D 或 E.24-氧代衍生物这被证明通过二维核磁共振数据分析,特别是通过由惠丰从 H 22 到C-24 ; 相关性从 H2-23-C-24 岁。从 H 26b (δH 5.85) C 24、 C-25,和我-27 ;H3 27 C 24、 C-25,和 C-26 日。由 ROESY 证明 7 相对的配置。H-3/H3-28 之间的相关性表明 H 3 α oriented.10 因此,inonotusol G 被指定为 3β,22-dihydroxy-5α-lanosta-8,25-dien-24-one。我们试图确定 C 22 由应用程序的绝对构型
改性的思迪方法 3 但失败。(S) 的导数-或羟基于 C-22 (R)-年产量酯无法获得从 7 使用 (−)-或 (+)-MTPACl (α-甲氧基-α trifluoromethylphenylacetyl 氯) 由搅拌 atroom 温度为 24 小时或 30 分钟,60℃ 加热。C 24 含羰基基团与 C 22 羟基的氢键效应可能已经阻碍了反应。